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B.E.D. Calculator (v. 1.0)
K&B Innovations опубликовал приложение 2012-08-20
(обновлено 2012-08-20)
Using the LQ method, the B.E.D. Calculator allows you to compare up to three different fractionation schemes in one view. Either select a structure from the drop down list with a predefined α/β ratio and endpoint or input your own custom α/β ratio. The B.E.D. Calculator is a great tool for both the student and the practitioner for evaluating dose schemes quickly when a computer may not be nearby.
First, select the desired organ with predefined α/β ratio or input your own custom α/β ratio. Next input a dose per fraction and then a total number of fractions. Select the “Add Course” button and the B.E.D. is automatically displayed below. Input up to three different dose schemes in one view and view the resulting B.E.D. instantly. Having three different schemes available at once will allow you to compare the doses delivered for varying dose rates and decide their effectiveness. The B.E.D. Calculator will also automatically sum all courses in one view should you wish to view a cumulative dose to a structure perhaps given dose in previous courses of therapy.
The B.E.D. Calculator will allow up to three different dose schemes on one view and will also let you add two more additional views to calculate B.E.D.’s. The calculations do not persist. Any data you input will be cleared once the program is stopped. The data however will remain there for you to view as long as you do not manually close the application. The α/β ratio can be changed from course to course within a view; however you must remember that any summations with different α/β ratios are not correct. The summation feature only adds the resulting numbers in a column and therefore only provides a valid number when α/β ratios used for each course are the same. An instance where this may be useful could be if a person received “X” dose of radiation to their spinal cord from previous XRT. You could input the dose to the spinal cord delivered for the previous treatments and then input the additional dose the proposed treatment would give the spinal cord using the spinal cord α/β ratio. The summation of the proposed total dose to spinal cord could then be viewed and then compared to a published lifetime allowance to help determine if the retreatment course could be used.
Each course that is input will not be calculated until the “Add Course” button is selected. By selecting the “Remove Course” button, the last course entered is cleared. There is also a soft key feature that will clear all courses on the current view or all courses on all three views. The α/β ratios and endpoints used for the organs listed are averages of published data and may not be the precise ratio you would like to use for your purposes. Selecting the “Custom” organ feature from the list will allow you to type in your own a/b ratio to be used in the calculation. Also, a α/β ratio of 10 for Tumor dose is the default selection as most calculations would probably be done to determine tumor dose.
The results provided by the B.E.D. Calculator should not be used as the sole determination of any treatment of a patient. The B.E.D. Calculator should be used as a teaching tool and a comparison tool for fractionation schemes. The user should understand the limitations of the LQ method as it relates to dose schemes and use the information provided by the B.E.D. Calculator appropriately.
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